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    Tier One Projects
    Zuo Lab

    Glia's role in synapse plasticity

    The nervous system comprises two classes of cells: neurons and glia. For a long time, neurons have been considered to be the sole basis for information integration, while glia have been thought to play a merely supportive role.  However, this dogma is now being challenged.  Recent studies show that
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    Recent Activity:
    Feb 26, 2020
    Zuo Lab

    Cellular mechanism of spine dynamics

    The majority of excitatory glutamatergic synapses in the mammalian central nervous system (CNS) are located on postsynaptic dendritic spines, which contain all the essential components required for postsynaptic signaling and thus serve as a good indicator of synaptic connectivity.  Many lines of in
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    Feb 26, 2020
    Zuo Lab

    Synapse remodeling in learning and memory formation

    Novel motor skills are learned through repetitive practice and, once acquired, can persist long after training stops.  Earlier studies have shown that such learning induces a change in functional map in the primary motor cortex.  However, how motor learning affects neuronal circuitry at the level of
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    Feb 26, 2020
     

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